Melaleuca interioris is a plant in the myrtle family, Myrtaceae and is endemic to Western Australia, South Australia, Queensland, New South Wales and the Northern Territory. It was formerly included in Melaleuca uncinata and is similar to that species with its cylinder-shaped leaves and small heads of yellow flowers, but with smaller, less compressed fruiting capsules.
This melaleuca occurs in the central parts of Western Australia, the central parts of South Australia, the southern half of the Northern Territory, far west of New South Wales and the far south-west corner of Queensland. It grows in shrubland in red sand on the edges of salt lakes, and near ephemeral creeks, claypans and floodplains.